Subjective feelings and changes in body sway following diazepam in sons of alcoholics and control subjects.
نویسندگان
چکیده
The possible generalization to diazepam of the dampened response to ethanol in sons of alcoholic fathers was evaluated in 62 sons of alcoholics (family history positive [FHP] subjects) and 62 family history negative (FHN) controls (124 men). Following challenges with placebo, .12 and .2 mg/kg of diazepam in three separate sessions, evaluation of subjective feelings and increases in body sway revealed no decreased reaction for FHPs.
منابع مشابه
The level of response to alcohol in daughters of alcoholics and controls.
BACKGROUND The low level of response (LR) to alcohol is a genetically influenced characteristic related to the development of alcohol use disorders (AUDs). This phenotype is found in men with a family history (FH) of alcoholism, predicts future AUDs, and has heritabilities as high as 60%. However, despite evidence of genetic influences for AUDs in both sexes, the majority of studies evaluating ...
متن کاملAnesthesia and Sedation in Chough (Pyrrhocorax pyrrhocorax) Following Intranasal Administration of Diazepam, Midazolam, Xylazine with or without Ketamine: Clinical Evaluation
Objective- This study aimed to compare sedation efficacy in intranasal administration of xylazine, diazepam and midazolam with or without ketamine in Chough. Design- To determine the sedation efficacy, an experimental in vivo study was employed. Animals- Seven healthy Choughs were examined in the current study. Procedu...
متن کاملCentral effects of the diuretic, bendrofluazide.
1. Central effects of the diuretic, bendrofluazide (2.5, 5 and 10 mg) were studied in 12 healthy volunteers. Two placebos and an active control drug, oxazepam (15 mg), were included. Single doses were administered double-blind at 10.00 h. The effects of drugs on performance and subjective feelings were assessed before and from 1.5-2.5 and 3.5-4.5 h after ingestion, and recording of the electric...
متن کاملRelationship of physical distress to dizziness in patients with fibromyalgia.
CONCLUSIONS The feelings of dizziness and unsteadiness of the patients with fibromyalgia supposed specifically amplified by the hypersensitivity mechanism of CSS (central sensitivity syndrome) of them. The severity of subjective pain and physical distress according to the questionnaires were not correlated with the objective body sway on the stabilometer. OBJECTIVES Fibromyalgia manifests pri...
متن کاملPharmacokinetics of ethanol in saliva: comparison with blood and breath alcohol profiles, subjective feelings of intoxication, and diminished performance.
The concentration-time profiles of ethanol were determined for capillary blood, end-expired breath, and saliva after 21 healthy men ingested ethanol at 0.68 g/kg body weight. Near the time of obtaining body fluids, the volunteers estimated their feelings of intoxication, and body sway (with open and closed eyes), hand tremor, positional alcohol nystagmus (PAN), and roving ocular movements (ROM)...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
- Journal of studies on alcohol
دوره 52 6 شماره
صفحات -
تاریخ انتشار 1991